Each box of 10 vials carries a Peptworks label and a unique QR → the batch CoA (HPLC + heavy metals), verified by a third party. Checkable by you and your customers.
🔗 Peptworks.euMelanotan I
| Units (combined total) | Discount | €/vial | This product ×100 |
|---|---|---|---|
| 100 | — | €20,00 | €2000 |
| 300 | −18% | €16,40 | €4920 |
| 500 | −25% | €15,00 | €7500 |
| 1000 | −32% | €13,60 | €13.600 |
Combine any reference: the discount applies to the combined total of vials, not per product. A single tier, not stacked.
What is — Melanotan I
Melanotan I (also known as afamelanotide, [Nle4, D-Phe7]-alpha-MSH or NDP-alpha-MSH) is a synthetic 13-amino-acid analog of alpha-melanocyte-stimulating hormone (alpha-MSH), supplied by Peptworks as a lyophilized 10 mg vial for Research Use Only. Substitutions of norleucine at position 4 and D-phenylalanine at position 7, together with terminal modifications, give the molecule greater enzymatic stability and prolonged receptor occupancy than native alpha-MSH. It is offered B2B from EU stock as unbranded bulk vials or white-label under a reseller's own brand, at >=98% HPLC purity with an independent per-batch Certificate of Analysis. It is not a medicine, supplement, cosmetic or medical device, and is not for human or animal consumption.
In research models, Melanotan I acts as a potent agonist at the melanocortin-1 receptor (MC1R); it is a non-selective melanocortin agonist that also binds other receptor subtypes (MC3R-MC5R), with high activity at MC1R. Receptor activation stimulates the intracellular cyclic AMP (cAMP) signaling cascade in melanocyte cultures, which in turn influences microphthalmia-associated transcription factor (MITF) activity and tyrosinase, the rate-limiting enzyme in melanin synthesis. In cell-based studies this pathway is associated with increased eumelanin production relative to pheomelanin. All description here refers strictly to in-vitro and preclinical experimental systems, not to any effect in humans.
Research
- Melanocortin receptor (MC1R) pharmacology and receptor-ligand binding studies
- Melanogenesis signaling in cultured melanocytes (cAMP-MITF-tyrosinase axis)
- Eumelanin versus pheomelanin synthesis in cell models
- Photoprotection and UV-response research in cell and animal models
- Structure-activity relationship studies of alpha-MSH analogs
- Peptide stability and enzymatic-degradation resistance assays
Advantages
- Serves as a well-characterized reference agonist at the melanocortin-1 receptor (MC1R) for melanocortin pathway research
- Enhanced enzymatic stability and prolonged receptor occupancy versus native alpha-MSH in experimental systems
- In vitro association with increased melanin (eumelanin) synthesis in melanocyte cultures
- Useful positive control in structure-activity relationship and receptor-binding assays
- Consistent >=98% HPLC purity supports reproducible experimental conditions across batches
Safety
- As a research reagent handled in the laboratory, Melanotan I has no established human safety profile from Peptworks and is not administered to people or animals
- Research literature on melanocortin analogs commonly discusses pigmentation-related endpoints and receptor cross-reactivity as experimental observations, not human outcomes
- Standard laboratory handling precautions for lyophilized peptides apply (avoid inhalation, skin and eye contact; reconstitute and store per protocol)
- No claims are made regarding safety or effects in humans; the product is Research Use Only
Ideal for
- Academic and commercial laboratories studying MC1R and melanocortin signaling
- Melanogenesis and pigmentation cell-culture research
- Photobiology and UV-response experimental models
- Structure-activity relationship and peptide-stability method development
- Resellers building an EU-stock research-peptide catalog in bulk or white-label
This product is a laboratory reagent supplied strictly for research. It is not a medicine, food or supplement and is not for human or veterinary use. It must be handled by qualified professionals under laboratory conditions.
Frequently asked questions
Where can I buy Melanotan I in bulk in the EU?
Peptworks supplies Melanotan I (10 mg lyophilized vials) wholesale from stock already inside the EU, so orders ship intra-community in 3-5 business days with no customs. It is a B2B research-reagent supply for resellers and labs, not a consumer shop. Minimum order is 10 units (one box) per reference, available as unbranded bulk vials or white-label under your own brand. Sold for Research Use Only (RUO).
What is the wholesale price per vial of Melanotan I?
Public per-vial pricing uses a single tier set by the combined total units across your whole order: EUR 15.00/vial at 100 units (base), EUR 12.30/vial at 300 units (-18%), EUR 11.25/vial at 500 units (-25%) and EUR 10.20/vial at 1000 units (-32%). The discount is one tier by combined volume, not stacked. Payment is by USDC bank transfer/invoice; there is no card checkout.
Can I order Melanotan I white-label under my own brand?
Yes. Peptworks offers Melanotan I two ways: unbranded bulk vials, or white-label labelled with your own brand and boxed. A one-time label setup fee of EUR 180 applies to orders under 100 units and is free from 100 units. Vials ship in boxes of 10 and the box carries a unique QR linking to that batch's Certificate of Analysis.
What is the minimum order for Melanotan I?
The minimum order is 10 units (one box) per reference. Vials ship in boxes of 10. You can reach a higher combined-volume discount tier by adding units across references in the same order, since the discount is calculated on the combined total units.
How is the Certificate of Analysis verified?
Every batch ships with an independent per-batch Certificate of Analysis (CoA) covering HPLC purity (>=98%) and heavy metals. The box carries the Peptworks label plus a unique QR that links to that specific batch's CoA, verifiable through Peptworks. This lets your own downstream buyers confirm authenticity per batch.
Is Melanotan I from Peptworks for human use?
No. Melanotan I is supplied strictly as a laboratory research reagent, Research Use Only (RUO). It is not a medicine, supplement, cosmetic or medical device and is not for human or animal consumption. Peptworks sells B2B to resellers and research organisations only, not to end users.