Each box of 10 vials carries a Peptworks label and a unique QR → the batch CoA (HPLC + heavy metals), verified by a third party. Checkable by you and your customers.
🔗 Peptworks.euIGF-1 LR3
| Units (combined total) | Discount | €/vial | This product ×100 |
|---|---|---|---|
| 100 | — | €55,00 | €5500 |
| 300 | −18% | €45,10 | €13.530 |
| 500 | −25% | €41,25 | €20.625 |
| 1000 | −32% | €37,40 | €37.400 |
Combine any reference: the discount applies to the combined total of vials, not per product. A single tier, not stacked.
What is — IGF-1 LR3
IGF-1 LR3 (Insulin-like Growth Factor 1 Long R3), supplied by Peptworks as a lyophilised 1 mg vial, is a laboratory research reagent for in-vitro and preclinical use only. It is an engineered analogue of native IGF-1 in which the third-position glutamic acid is substituted with arginine (R3) and a 13-amino-acid N-terminal extension is added, altering its interaction with IGF-binding proteins. It is a research reagent only — not a medicine, supplement, cosmetic or medical device, and not for human or animal consumption. Purity is ≥98% by HPLC with an independent per-batch Certificate of Analysis.
In laboratory research models, IGF-1 LR3 is studied as an agonist of the IGF-1 receptor (IGF-1R). The arginine substitution and N-terminal extension are reported in the literature to markedly reduce binding to IGF-binding proteins (IGFBPs) compared with native IGF-1, which in experimental systems is associated with a longer functional half-life and greater availability of free peptide to engage the receptor in culture. Downstream, IGF-1R engagement activates intracellular signalling cascades such as the PI3K/Akt and Ras/MAPK pathways, which are the object of study in cell-signalling and proliferation research. All mechanistic description here refers strictly to in-vitro and animal research models.
Research
- Cell proliferation and viability assays in cultured cell lines
- IGF-1R signal-transduction research (PI3K/Akt and Ras/MAPK pathways)
- Myoblast and skeletal-muscle cell differentiation models
- Cell-culture media supplementation and serum-free culture development
- Growth-factor receptor binding and IGFBP-interaction studies
- Metabolic and glucose-uptake research in in-vitro systems
Advantages
- In cell-culture models, studied for its capacity to support proliferation of cultured cell lines
- Reported in research systems to have reduced IGFBP binding versus native IGF-1, useful for isolating receptor-level effects
- Associated in experimental conditions with an extended functional half-life relative to native IGF-1
- Characterised in vitro as a potent IGF-1R agonist for signal-transduction studies
- Consistent, CoA-backed lots (≥98% HPLC) support reproducibility across experiments
Safety
- This is a laboratory reagent; the following are observations reported in preclinical and in-vitro research literature, not human effects.
- In animal research models, elevated IGF-1-axis signalling has been associated with hypoglycaemia-related metabolic changes
- Animal-model studies report tissue and organ growth changes under sustained IGF-1R activation
- In-vitro over-stimulation has been linked in the literature to receptor desensitisation in cultured cells
- Handle as a research chemical using appropriate laboratory safety practices; not evaluated for safety in humans or animals
Ideal for
- Cell-culture and molecular-biology laboratories running proliferation or differentiation assays
- Academic and preclinical research groups studying IGF-1R signalling
- Contract research organisations (CROs) needing consistent, CoA-backed reagent lots
- Distributors and white-label brands building an EU research-peptide catalogue
- Assay-development and formulation teams requiring reproducible media supplementation
This product is a laboratory reagent supplied strictly for research. It is not a medicine, food or supplement and is not for human or veterinary use. It must be handled by qualified professionals under laboratory conditions.
Frequently asked questions
Where can I buy IGF-1 LR3 in bulk in the EU?
Peptworks supplies IGF-1 LR3 (1 mg lyophilised) wholesale to B2B buyers from stock already held inside the EU. Orders ship as intra-community consignments in roughly 3-5 business days with no customs clearance. Minimum order is 10 units (one box) per reference, available as bulk unbranded vials or white-labelled with your own brand. Research Use Only; not for human or animal consumption.
What is the wholesale price per vial of IGF-1 LR3?
IGF-1 LR3 (1 mg) starts at EUR 49.00 per vial at the 100-unit tier. Pricing follows a single tier set by combined order volume, not stacked discounts: 300 units = EUR 40.18/vial (-18%), 500 units = EUR 36.75/vial (-25%) and 1,000 units = EUR 33.32/vial (-32%). Because the tier is based on the combined total units across your whole order, a mixed peptide basket can reach a better price than buying one reference alone.
Can I order white-label IGF-1 LR3 with my own brand?
Yes. Peptworks offers two formats: bulk unbranded vials, or white-label vials labelled with your own brand and boxed ready to list. A one-time label setup fee of EUR 180 applies to orders under 100 units and is waived from 100 units upward. Every box carries a unique QR code linking to that batch's Certificate of Analysis.
What is the minimum order for IGF-1 LR3?
The minimum order is 10 units (one box) per reference. Vials ship in boxes of ten, and each box carries the Peptworks label with a unique batch QR code. There is no upper limit, and combined volume across references unlocks the -18%, -25% and -32% pricing tiers.
How is the IGF-1 LR3 Certificate of Analysis verified?
Each batch is released with an independent, per-batch Certificate of Analysis covering HPLC purity (≥98%) and heavy-metals testing. The box carries a unique QR code that links to that specific batch's CoA, which can be independently verified through Peptworks — a traceable trust signal you can pass on to your own customers.
How does Peptworks ship and how do I pay?
Stock is held inside the EU, so orders move as intra-community shipments in about 3-5 business days with no customs. Payment is by USDC bank transfer / invoice; there is no card checkout on site, which suits procurement and accounts-payable workflows. The full site is available in ten languages (ES, EN, DE, FR, PT, IT, NL, PL, CS, EL).