Each box of 10 vials carries a Peptworks label and a unique QR → the batch CoA (HPLC + heavy metals), verified by a third party. Checkable by you and your customers.
🔗 Peptworks.euAICAR
| Units (combined total) | Discount | €/vial | This product ×100 |
|---|---|---|---|
| 100 | — | €30,00 | €3000 |
| 300 | −18% | €24,60 | €7380 |
| 500 | −25% | €22,50 | €11.250 |
| 1000 | −32% | €20,40 | €20.400 |
Combine any reference: the discount applies to the combined total of vials, not per product. A single tier, not stacked.
What is — AICAR
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide, also known as acadesine) is a small-molecule research compound supplied by Peptworks as a lyophilised 50 mg vial for laboratory use. It is a widely used pharmacological AMPK activator in metabolic and cellular-energy research. Peptworks stocks it inside the EU for B2B Bulk unbranded vials supply, at >=98% HPLC purity with an independent per-batch Certificate of Analysis. Research Use Only: not for human or animal consumption, and not a medicine, supplement, cosmetic or medical device.
AICAR is a cell-permeable adenosine analogue that is phosphorylated intracellularly to ZMP, a mimetic of AMP. ZMP allosterically activates AMP-activated protein kinase (AMPK), a central sensor of cellular energy status. In research models, AMPK activation is studied for its downstream effects on glucose uptake, fatty-acid oxidation, mitochondrial biogenesis and the mTOR and PGC-1alpha signalling axes. These mechanisms are characterised strictly in vitro and in animal models and are the reason AICAR is a common reference tool in metabolic and longevity-related cell biology.
Research
- AMPK signalling and cellular energy-sensing pathways
- Glucose uptake and insulin-signalling models in vitro
- Mitochondrial biogenesis and oxidative metabolism
- Skeletal-muscle metabolism and exercise-mimetic research
- mTOR / autophagy and longevity-related cellular pathways
- Metabolic-disease preclinical model characterisation
Advantages
- Serves as a well-characterised reference AMPK activator for in-vitro and animal metabolic studies
- Enables reproducible activation of AMPK-dependent pathways in cell-based assays
- Widely cited exercise-mimetic tool compound for skeletal-muscle metabolism research
- Useful positive control for mitochondrial-biogenesis and fatty-acid-oxidation experiments
- Supports longevity and energy-metabolism pathway research in preclinical models
Safety
- As a research reagent it has no approved human use; the following are observations reported in preclinical literature, not human effects
- Accumulation of ZMP can perturb AMP-independent metabolic pathways in cell models
- Reported off-target effects on nucleotide metabolism in some in-vitro systems
- Variable AMPK-independent actions described depending on cell type and concentration
- Handle as a laboratory chemical using appropriate PPE; toxicological profile in research settings is dose- and model-dependent
Ideal for
- Academic and industrial labs studying AMPK and cellular energy metabolism
- Resellers building a longevity/metabolic research-reagent catalogue
- Assay-development teams needing a consistent AMPK-activator reference compound
- White-label brands supplying research peptides and small molecules in the EU
- Distributors requiring EU-stocked, CoA-backed bulk supply
This product is a laboratory reagent supplied strictly for research. It is not a medicine, food or supplement and is not for human or veterinary use. It must be handled by qualified professionals under laboratory conditions.
Frequently asked questions
Where can I buy AICAR in bulk in the EU?
Peptworks supplies AICAR (50 mg lyophilised vials) in bulk from stock held inside the EU, so orders ship intra-community in 3-5 business days with no customs. You can order unbranded bulk vials or white-label boxes under your own brand. Sold for Research Use Only to B2B resellers, not to end users.
What is the wholesale AICAR price per vial?
AICAR 50 mg starts at EUR 22.00/vial at the 100-unit tier. Combined-volume pricing on the whole order lowers the per-vial price: 300 units EUR 18.04 (-18%), 500 units EUR 16.50 (-25%), and 1000 units EUR 14.96 (-32%). Discounts follow a single tier based on your combined total units and are not stacked.
Can I get AICAR white-labelled with my own brand?
Yes. Peptworks offers white-label AICAR: vials labelled with your brand and boxed. The box carries a unique QR that links to that batch's Certificate of Analysis. A one-time label setup fee of EUR 180 applies to orders under 100 units and is free from 100 units. Alternatively, order unbranded bulk vials.
What is the minimum order for AICAR?
The minimum order is 10 units (1 box) per reference. Vials ship in boxes of 10, and each box carries the Peptworks label plus a unique QR linking to that batch's CoA. You can combine references, and volume discounts apply to the combined total units across the order.
How is the AICAR Certificate of Analysis verified?
Every batch ships with an independent Certificate of Analysis covering HPLC purity (>=98%) and heavy metals. The box carries a unique QR that links to that specific batch's CoA, verifiable through Peptworks, so your customers can confirm provenance and identity for each lot.
How do I pay and how fast does AICAR ship within the EU?
Payment is by USDC bank transfer against invoice; no card payment on the site. Because stock is already inside the EU, orders ship intra-community in 3-5 business days with no customs clearance. This applies to both Bulk unbranded vials AICAR orders for B2B resellers.